Hybrid Cytometry
seeing new dimensions

Get combined readouts on live‑then‑fixed cells. Stop losing cells by using our gentle staining.

1 Bench
Footprint
1 Day
Training
1 Click
Assay Operation
Compact hybrid cytometry platform on laboratory bench, with automated liquid handling system and fluorescent cell scanner

Imaging cytometry for live‑then‑fixed cells

Our automated bioassay exposes cells to a programmed sequence of treatments, staining reagents, and fluorescent cell scanning cycles

Fluorescence microscopy

Serial treatments and scans
Dynamic live-cell data

Gentle in situ staining

Cell fixation in situ
Stain-Wash-Scan cycles

High-level analysis

Imaging and cytometry data
Gating, histograms, dotplots

Applications

  • Automate complex bioassays
  • Screen T-cell cancer antigens
  • Combine dynamic killing with phenotyping
  • In-depth MOA for the bispecific antibodies
Laboratory scientist analyzing colorful flow cytometry data on multiple computer screens with cell culture samples

Frequently Asked Questions

What is Hybrid Cytometry?

Hybrid Cytometry is a new fully automated research method that brings together the tracking of live-cell dynamics and an analysis of multiple makers of the cells stained post fixation. Our aim is to add a new meaningful data layer, and automate complex 2-day cell-based experiments. Would you like to watch a demo video? Please fill out the request form.

Which basic applications run without "Hybrid" capabilities?

Our system’s applications include targeted delivery, GFP expression, cytotoxicity, killing, and proliferation assays. Unlike current approaches, where dynamic cellular responses or gene expression would be studied with live-cell imaging, and phenotypes would be analysed using flow cytometry, our system allows one automated assay for both readouts combined.

Is your system available for testing or for purchase?

We begin with an exploratory call and a brief 10-week service project that allows both parties to validate the system’s usefulness for the specific application. It is a paid project, but we are discounting its cost to stay below the market price for similar efforts, accounting for the risks involved. If you like the generated data, we will explain the further demo or purchasing options.

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